Fig. 3.

Expression of the mRNAs encoding iron-related proteins and proinflammatory cytokines in the pancreas. Fpn1(+IRE), Hamp, Dmt1(+IRE), Tfrc, IL-1β, IL-6, and TNF-α mRNA expression in the pancreas of WT, Heph/Cp KO, Cp KO, and Heph KO mice is shown (n = 6 per group). Values were normalized to GAPDH expression and expressed as a proportion of the WT control value. Data are shown as mean ± SEM. Bars without common letters are significantly different (p < 0.05, as determined by one way ANOVA followed by Tukey's multiple comparisons test).