Fig. 3.

Effect of 24-OH on the levels of acetylated, phosphorylated, and total tau in SK-N-BE cells. (A) Acetyl-tau, phospho-tau, and total tau levels were analyzed in cells treated with 24-OH. Each blot shown is representative of 3 experiments. The histograms represent mean values ± SD of 3 experiments. Densitometric measurements were normalized against the corresponding α-tubulin levels and expressed as percentage of control value. *P < 0.05 and ***P < 0.001 vs control. (B) Phospho-tau/tau ratio derived from densitometric measurements. *P < 0.05 and **P < 0.01 vs control.