Fig. 4.

Effect of 7-K on the levels of acetylated, phosphorylated, and total tau in SK-N-BE cells. (A) Acetyl-tau, phospho-tau, and total tau levels were analyzed in cells treated with 7-K. Each blot shown is representative of 3 experiments. The histograms represent mean values ± SD of 3 experiments. Densitometric measurements were normalized against the corresponding α-tubulin levels and expressed as percentage of control value. (B) Phospho-tau/tau ratio derived from densitometric measurements.