Fig. 1. Formation of peptide diastereomers Ac-l-Tyr(Me)-l-Leu-NH2 and Ac-d-Tyr(Me)-l-Leu-NH2 by the reaction of 1 mM racemic 5(4H)-oxazolone 2a with 5 mM H-l-Leu-NH2 in 100 mM MOPS buffer (pH 7.2), at room temperature, in the presence of different concentrations of decanoic acid (DA). The effects are reported in terms of the relative total yield of the dipeptide (left axis, black filled circles) and of the diastereomeric ratio (right axis, red open squares).
