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. 2017 Jun 30;2017(1):nix016. doi: 10.1093/nc/nix016
Neurocognitive networks implicated in self-representation
Network Key nodes Aspects of self-representation Result of down-regulation Relevant studies
Default Mode Network (DMN) Posterior cingulate cortex (PCC), medial prefrontal cortex (MPFC), inferior parietal lobule (IPL) Narrative self; mental time-travel; judgement, planning, and goals Dissolution of narrative/cognitive self (personality, history, goals, ownership of thoughts); compromised binding of embodied to narrative representations Carhart-Harris et al. (2012); Palhano-Fontes et al. (2015); Bouso et al. (2015); Tagliazucchi et al. (2016); Speth et al. (2016)
Salience Network (SLN) Anterior cingulate cortex (ACC), anterior insular cortex (AIC) Embodied self; emotional feeling; salience Dissolution of embodied self (changes to body boundaries, spatial self-location, personal relevance of emotional feelings) Lebedev et al. (2015); Tagliazucchi et al. (2016)