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. 2018 Jun 15;11:3485–3494. doi: 10.2147/OTT.S158355

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© 2018 Hong et al. This work is published and licensed by Dove Medical Press Limited

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RPN2 expression in NPC tissues and siRNA-RPN2 inhibited cell proliferation of NPC cells. (A) mRNA expression of RPN2 in 68 NPC tissues and adjacent normal tissue was determined by RT-PCR. (B) Protein expression of RPN2 in NPC tissues and adjacent normal tissue was identified by IHC analysis. Expression of RPN2 was down-regulated in both CNE2 (C) and HNE1 (D) cells. Cell proliferation in CNE2 (E) and HNE1 (F) cells was detected by CCK-8 assay.

Notes: Data were presented as mean±SD, *P<0.05, **P<0.01 compared with the control group.

Abbreviations: RPN2, ribophorin II; NPC, nasopharyngeal carcinoma; RT-PCR, reverse transcription polymerase chain reaction; IHC, immunohistochemistry; CCK-8, cell counting kit-8; SD, standard deviation; OD, optical density.