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. 2018 Jun 15;11:3485–3494. doi: 10.2147/OTT.S158355

Figure 5.

Figure 5

Figure 5

Effect of siRNA-RPN2 on expressions of caspase-3, caspase-9, E-cadherin, and MMP2 and the phosphorylation of PI3K/AKT. (A and B) After 48 h of siRNA-RPN2 treatment, the protein levels of caspase-3, caspase-9, E-cadherin, and MMP2 in CNE2 and HNE1 cells were analyzed by Western blot. (C and D) The phosphorylation of PI3K/AKT in CNE2 and HNE1 cells was analyzed by Western blot. GAPDH also detected as the control of sample loading.

Note: Data were presented as mean±SD, *P<0.05, **P<0.01 compared with the control group.

Abbreviations: RPN2, ribophorin II; OD, optical density; SD, standard deviation.