Table 2.
Self-reported adverse events in imatinib
Adverse events | Glivec® n=267 | % | Xinwei® n=68 | % | P-value |
---|---|---|---|---|---|
Nausea and vomiting | 104 | 39 | 23 | 34 | 0.437a |
Diarrhea | 79 | 29 | 16 | 24 | 0.322a |
Joint pain | 70 | 26 | 13 | 19 | 0.226a |
Edema | 59 | 22 | 11 | 16 | 0.284a |
Skin problems | 54 | 20 | 16 | 24 | 0.550a |
Muscle cramps | 48 | 18 | 14 | 21 | 0.621a |
Conjunctivitis | 34 | 13 | 7 | 10 | 0.584a |
Stomatitis | 21 | 8 | 4 | 6 | 0.579a |
Headache | 20 | 7 | 7 | 10 | 0.448a |
Abdominal pain | 13 | 5 | 1 | 1 | 0.316b |
Hearing loss | 11 | 4 | 3 | 4 | 1.000b |
Memory loss | 5 | 2 | 2 | 3 | 0.633b |
Spasm | 5 | 2 | 0 | 0 | 0.587b |
Dizziness | 4 | 1 | 0 | 0 | 0.586b |
Fever | 0 | 0 | 2 | 3 | 0.041b |
Cough | 0 | 0 | 5 | 7 | <0.001b |
None | 48 | 18 | 15 | 22 | 0.442a |
Notes:
Pearson’s chi-square test;
Fisher’s exact test. Bold data indicate statistically significant with p-value < 0.05.