Table 3.

Effects of collaborative interventions between pharmacists and physicians (N=152) on the individual domains in MAI at 6 months

Domains in MAI	Difference in MAI scores (baseline–month 6)		z value (Mann–Whitney U test)	p-value
	Intervention group, n=73	Control group, n=79
Correct indication			−4.761	<0.001**
Median (IQR)	0 (3)	0 (0)
Range	−3 to 24	−6 to 3
Mean rank	91.22	62.90
Effectiveness			−2.063	0.039*
Median (IQR)	0 (0)	0 (0)
Range	−3 to 9	−6 to 3
Mean rank	81.27	72.09
Correct dosage			−4.637	<0.001**
Median (IQR)	2 (4)	0 (4)
Range	−4 to 10	−6 to 7
Mean rank	93.25	61.02
Correct direction			−4.950	<0.001**
Median (IQR)	0 (2)	0 (0)
Range	−4 to 8	−6 to 6
Mean rank	92.41	61.80
Practical direction			−4.388	<0.001**
Median (IQR)	0 (1)	0 (0)
Range	−1 to 4	−3 to 2
Mean rank	90.46	63.60
Drug–drug interaction			−2.280	0.023*
Median (IQR)	0 (2)	0 (0)
Range	−4 to 10	−8 to 8
Mean rank	84.06	69.51
Drug–disease interaction			−2.970	0.003**
Median (IQR)	0 (2)	0 (0)
Range	−6 to 8	−6 to 6
Mean rank	86.40	67.35
Duplication of drug			−2.844	0.004**
Median (IQR)	0 (0)	0 (0)
Range	−1 to 8	−2 to 8
Mean rank	83.08	70.42
Duration of therapy			−5.284	<0.001**
Median (IQR)	1 (1)	0 (1)
Range	−1 to 8	−2 to 6
Mean rank	94.78	59.61
Cost of medication			−5.787	<0.001**
Median (IQR)	1 (2)	0 (1)
Range	−1 to 4	−5 to 3
Mean rank	96.61	57.92

Notes:

^*p<0.05;

^**p<0.01.

Abbreviations: IQR, interquartile range; MAI, Medication Appropriateness Index.