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. 2018 Mar 15;46(10):4950–4965. doi: 10.1093/nar/gky196

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Ehmt1^+/− and Ehmt2^+/− comparative analysis of repressive histone marks. (A) Clustering of the regions with significant (P< 0.001) H3K9me3 or H3K27me3 deregulations in Ehmt1^+/− or Ehmt2^+/− samples. Left: Pie chart size representing the size of each cluster in terms of base pairs covered, genome-wide. Right: Centroids mean, 25th and 75th percentiles for clusters C1–4. For each cluster the total amount of regions and their total length (size in base pairs) is indicated. Only in 15% of regions (C1) Ehmt2^+/− displays an increase of H3K9me3 comparable to Ehmt1^+/−. Changes in H3K27me3 are negligible (C4, 2%). (B) Example of H3K9me3 tracks. Average +/- SEM of a region formed by elements of C1 and C2 and encompassing several olfactory receptors (from Olfr697 to Olfr711, not shown).