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BDNF/TrkB signaling pathway modulates Munc18-1 phosphorylation under muscle contraction conditions. Representative Western blot bands and quantification show that both exogenous BDNF and 47/TrkB significantly decrease pMunc18-1 levels after stimulation resulting in contraction. Moreover, exogenous BDNF decreases Munc18-1 levels under these conditions. Data are mean percentage ± SEM, *p < 0.05 (n = 5).
