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. 2018 Jun 12;11:207. doi: 10.3389/fnmol.2018.00207

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Copyright © 2018 Simó, Just-Borràs, Cilleros-Mañé, Hurtado, Nadal, Tomàs, Garcia, Lanuza and Tomàs.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relation between nPKCε and cPKCβI. (A) Representative Western blot bands and quantification show that both (βIV5-3/Ctrl: muscles in basal conditions vs. preincubated with βIV5-3 peptide) and (St+βIV5-3/St: synaptic activity compared with the βIV5-3 peptide), the ratio pnPKCε/nPKCε significantly increases. Moreover, in (St+βIV5-3/Ctrl+βIV5-3: basal conditions compared with stimulated samples; both treated with βIV5-3 peptide) both nPKCε and pnPKCε significantly increase. (B) Representative Western blot bands and quantification show that in both (εVI-2/Ctrl: muscles in basal conditions vs. preincubated with εVI-2 peptide) and (St+εVI-2/St: synaptic activity compared with the εVI-2 peptide) the cPKCβI total levels significantly decreased, being the ratio pcPKCβI/cPKCβI in this last condition significantly increased. Data are mean percentage ± SEM, ^*p < 0.05 (n = 5).