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. 2018 Apr 12;46(10):5159–5170. doi: 10.1093/nar/gky278

Table 2. Steady-state catalytic activity for unmodified and sumoylated TDG.

Enzyme Substrate v o (nM·min−1) k cat (min−1) k max/kcat
TDG fC 0.236 ± 0.011 (4.7 ± 0.3) × 10−3 359
TDG∼SUMO-1 fC 0.340 ± 0.036 (6.8 ± 0.7) × 10−3 12
TDG∼SUMO-2 fC 0.315 ± 0.022 (6.3 ± 0.5) × 10−3 12
TDG caC 0.363 ± 0.023 (7.3 ± 0.5) × 10−3 68
TDG∼SUMO-1 caC 0.356 ± 0.040 (7.1 ± 0.8) × 10−3 10
TDG∼SUMO-2 caC 0.354 ± 0.037 (7.1 ± 0.8) × 10−3 10