Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Immunoblot analysis of specific AKT array proteins from wild-type and HD mouse tissues. Specific AKT target proteins – ASK1, c-Jun, BCL-2, and GSK3beta – were evaluated for phosphorylation changes in brain caudate regions of HD mice. Lanes 1–3: Wild-type mice (n=3); Lanes 4–6: HD mice (n=3). Decreased phosphorylation consistent with the ORF2-overexpression effects were noted in the tissue samples.
