Figure 2.

Prenatal stress (PRS) mice exhibit the increased anxiety-like behaviors. CON and PRS represent control and PRS mice, respectively. (A and B) In the open field test (OFT), PRS mice spent less time in the center area compared with control mice. (C and D) In the elevated plus maze (EPM), PRS mice showed a decreased percentage of time spent in the open arms compared with control mice. (E and F) In the light/dark box test (DLT), PRS mice spent less time in the light-box compared with control mice. All bars represent means±SEM; 2-tailed Student’s t test; *P<.05 and **P<.01 between the data of control (n=14) and PRS mice (n=14).