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. 2018 Feb 20;21(6):570–581. doi: 10.1093/ijnp/pyy006

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© The Author(s) 2018. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — The basal activity of hypothalamo-pituitary-adrenal (HPA)-axis is potentiated in prenatal stress (PRS) mice. CON and PRS represent control and PRS mice, respectively. (A and B) PRS mice showed a significant increase in basal corticosterone (A) and adrenocorticotropin (ACTH) (B) concentrations. Sample collection was performed in the morning (8:00 am) and in the afternoon (6:00 pm). All bars represent means±SEM; 2-tailed Student’s t test; *P<.05 between the data of control (n=10) and PRS mice (n=12) at the same time.