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. 2018 Feb 20;21(6):570–581. doi: 10.1093/ijnp/pyy006

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© The Author(s) 2018. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — The anxiety-like behaviors in postnatal stress (PRS) mice are corrected by 5-aza-CdR. 5-aza-CdR recovered the shortened center time in the open field test (OFT) (A), improved the decrease in the percentage of time spent in the open arms of the elevated plus maze (EPM) (B), and increased the time in the light box (C) in PRS mice. All values are means±SEM; 2-way ANOVA followed by protected least significant difference (PLSD) posthoc test; *P<.05 and **P<.01 between the data of vehicle-treated control mice (n=14) and vehicle-treated PRS mice (n=14); #P<.05 between the data of vehicle-treated PRS mice (n=14) and 5-aza-CdR-treated PRS mice (n=16).