Table 4.

Top 10 biological processes affected in APM and TKA meniscus

Biological processes elevated in TKA meniscus	P value	FDR	Biological processes elevated in APM meniscus	P value	FDR
response to lipid	<0.0001	<0.0001	positive regulation of histone deacetylase activity	<0.0001	0.004
regulation of response to external stimulus	<0.0001	<0.0001	positive regulation of histone deacetylation	<0.0001	0.004
negative regulation of multicellular organismal process	<0.0001	<0.0001	positive regulation of endothelial cell chemotaxis by VEGF	<0.0001	0.004
cell migration	<0.0001	<0.0001	regulation of histone deacetylase activity	<0.0001	0.004
negative regulation of response to external stimulus	<0.0001	<0.0001	growth	<0.0001	0.004
regulation of multicellular organismal process	<0.0001	<0.0001	positive regulation of cell migration by VEGF signaling pathway	<0.0001	0.004
negative regulation of neuron differentiation	<0.0001	<0.0001	skeletal system development	<0.0001	0.004
regulation of fever generation	<0.0001	<0.0001	regulation of neuron apoptotic process	<0.0001	0.004
negative regulation of response to wounding	<0.0001	<0.0001	positive regulation of protein deacetylation	<0.0001	0.004
localization of cell	<0.0001	<0.0001	regulation of histone deacetylation	<0.0001	0.005

FDR = false discovery rate