Table 1.
Clinicopathologic characteristics of NMIBC cohorts
| Characteristics | Low-grade NMIBC (%), n = 23 |
High-grade NMIBC (%), n = 82 |
High-grade NMIBC treated BCG without maintenance (%), n = 62 |
|
|---|---|---|---|---|
| Median age (range) | 67 (25, 80) | 70 (36, 87) | 69.8 (37.3, 87.3) | |
| Sex | ||||
| Male | 13 (56) | 67 (82) | 51 (82) | |
| Female | 10 (43) | 15 (18) | 11 (18) | |
| Smoking | ||||
| Current | 3 (13) | 13 (16) | 9 (15) | |
| Former | 13 (57) | 46 (56) | 35 (56) | |
| Never | 7 (30) | 23 (28) | 18 (29) | |
| Stage | ||||
| Ta | 23 (100) | 32 (39) | 26 (42) | |
| Tis | 0 | 12 (15) | 12 (19) | |
| T1 | 0 | 38 (46) | 24 (39) | |
| No. of tumors | ||||
| Single | 18 (78) | 45 (55) | 33 (53) | |
| Multiple | 5 (22) | 37 (45) | 29 (46) | |
| Tumor size (cm) | ||||
| <3 | 16 (70) | 46 (56) | 36 (58) | |
| ≥3 | 7 (30) | 36 (44) | 26 (42) | |
| Concomitant CIS | ||||
| No | 23 (100) | 43 (52) | 30 (48) | |
| Yes | 0 (0) | 39 (47) | 32 (52) | |
| Treatment | ||||
| BCG | 3 (13) | 66 (80) | 62 (100) | |
| MMC | 9 (39) | 1 (1) | 0 (0) | |
| Observation | 11 (48) | 10 (12) | 0 (0) | |
| Immediate cystectomy | 0 (0) | 5 (6) | 0 (0) |
BCG = bacillus Calmette-Guérin; CIS = carcinoma in situ; MMC = mitomycin; MIBC = muscle invasive bladder cancer; NMIBC = nonmuscle invasive bladder cancer; TUR = transurethral resection.