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. Author manuscript; available in PMC: 2018 Sep 26.
Published in final edited form as: Lab Chip. 2017 Sep 26;17(19):3221–3233. doi: 10.1039/c7lc00623c

Table 1.

Intramural and interstitial flow rates and vessel diameters measured in healthy tissue using animal models, and in tumors using both animal and human models.

Healthy tissue Tumor
Intramural flow Arterioles: 29
diameter 15–60μm: 7–12 mm/s
Capillaries: 29
diameter 5μm: 0.2 mm/s
Venules: 29
diameter 18–72μm: 0.2–2.4 mm/s
Microlymphatic vessels: 38
diameter 100 μm: 1–7 mm/s
Lymphatic capillaries: 39, 155 diameter 55 μm: 0–29 μm/s
Blood vessels in mammary carcinoma: 156
diameter 7–63μm: 0–0.8 mm/s
Blood vessels in glioma:
diameter 8–55μm: 0–0.5 mm/s 156
diameter 1–100μm: 0.001–10 mm/s 157
Blood vessels in adenocarcinoma: 158
arterioles 9–10μm: 0.59–0.7 mm/s
capillaries 6–8μm: 0.09–0.27 mm/s
venules 10–26μm: 0.09–0.22 mm/s
Interstitial flow Rabbit ear tissue: 50
0.59±0.16 μm/s
VX2 carcinoma: 0.55 ± 0.16 μm/s 50
C6-pTET-VEGF tumor: 0.1–0.5 μm/s 159
Cervical carcinoma: 1–7 μm/s 55
Melanoma: 1–9 μm/s
Nonmetastatic squamous carcinoma: 5–25 μm/s
Metastatic squamous carcinoma: 10–55 μm/s