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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Placenta. 2018 Apr 11;65:55–64. doi: 10.1016/j.placenta.2018.04.003

Figure 4.

Figure 4

Analysis of the conservation of placenta-associated miRNA clusters between the macaque and human. A. Annotated miRNAs within the C14MC, C19MC and miR-371-3 clusters were assessed in macaque placentas. Comparison in expression between the human and macaque is represented by individual bars along the chromosome designated as either an ortholog but not expressed, expressed, highly expressed in first trimester placenta, highly expressed in term placenta, and not annotated or expressed but is an ortholog. Highly expressed refers to those that are significantly, differentially expressed. B. Expression of miRNAs within placenta-associated clusters across gestation. The mean log10TPM for each miRNA and the overall mean and SE for all miRNAs is represented for each time point. Significantly different (P < 0.0001) expression levels between first trimester and term placentas for the C14MC, C19MC and miR-371-3 cluster are denoted by an asterisk.