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. Author manuscript; available in PMC: 2018 Sep 22.
Published in final edited form as: N Engl J Med. 2018 Mar 22;378(12):1132–1141. doi: 10.1056/NEJMra1713301

Figure 1. Organ-specific Manifestations of Autoimmune Polyendocrine Syndromes.

Figure 1

The main manifestations of autoimmune polyendocrine syndrome type 1 (APS-1, red box), autoimmune polyendocrine syndrome type 2 (APS-2, blue box) and X-linked immunodysregulation polyendocrinopathy enteropathy (IPEX, green box). Primary adrenal insufficiency and type 1 diabetes are shared between APS-1 and −2, respectively (red-blue box); Type 1 diabetes is shared between Aps-2 and IPEX (blue-green box).