Table 2.

CSF/Plasma Inflammation and CSF Markers of AD Pathology

	CSF p-Tau		CSF-Aβ42		CSF sAPPβ
	Unstandardized Beta (Standard Error)		Unstandardized Beta (Standard Error)		Unstandardized Beta (Standard Error)
	95% Confidence Interval; t-value		95% Confidence Interval; t-value		95% Confidence Interval; t-value
	Plasma	CSF	Plasma	CSF	Plasma	CSF
IL-6	9.268 (4.989)	−1.993 (3.163)	38.301 (59.207)	−22.299 (37.530)	38.010 (59.063)	−29.342 (37.439)
	95% CI: −0.607 to 19.143; t=1.86	95% CI: −8.253 to 4.267; t=−0.63	95% CI: −78.886 to 155.489; t=0.65	95% CI= −96.581 to 51.984; t=−0.59	95% CI: −78.893 to 154.913; t=0.64	95% CI: −103.445 to 44.760; t=−0.78
IL-8	2.169 (0.702)**	0.401 (0.125)**	6.137 (8.771)	3.810 (1.560)**	23.466 (8.800)**	0.755 (1.566)
	95% CI: 0.782 to 3.556; t=3.09	95% CI: 0.155 to 0.648; t=3.22	95% CI: −11.205 to 23.480; t=0.70	95% CI: 0.726 to 6.894; t=2.44	95% CI: 6.066 to 40.867; t=2.67	95% CI: −2.34 to 3.850; t=0.48
IP-10	0.001 (.009)	0.022 (0.007)**	0.068 (0.113)	0.075 (0.086)	0.139 (0.117)	0.089 (0.089)
	95% CI: −0.017 to 0.020; t=0.15	95% CI: 0.008 to 0.0359; t=3.13	95% CI: −0.156 to 0.292; t=0.60	95% CI: −0.095 to 0.246; t=0.87	95% CI: −0.092 to .369; t=1.19	95% CI: −0.067 to 0.264; t=1.00
MCP-1	0.052 (0.029)	−0.004 (0.014)	0.189 (0.347)	−0.023 (0.169)	0.669 (0.340)*	0.268 (0.165)
	95% CI: −0.006 to 0.109; t=1.77	95% CI: −0.032 to 0.024; t=−0.31	95% CI: −0.498 to 0.876; t=0.54	95% CI: −0.357 to 0.3116; t=−0.13	95% CI: −0.002 to 1.341; t=1.97	95% CI: −0.059 to 0.594; t=1.62
MIP-1β	−0.058 (0.095)	1.541 (0.514)**	−0.334 (1.145)	4.978 (6.215)	−0.512 (1.152)	8.255 (6.253)
	95% CI: −0.245 to 0.129; t=−0.61	95% CI: 0.524 to 2.558; t=3.00	95% CI: −2.598 to 1.930; t=−0.29	95% CI: −7.312 to 17.268; t=0.80	95% CI: −2.790 to 1.767; t=−0.44	95% CI: −4.110 to 20.620; t=1.32

^*p < .05;

^**p< .01