Table 2. Univariate and multivariate COX regression analysis for overall survival in DLBCL patients.

	Overall Survival
	Univariate COX Regression		Multivariate COX Regression
	HR (IC 95%)	P	HR (IC 95%)	P
CXCR7 (+ vs -)	2.668 (1.080–6.592)	0.033 *	2.764 (1.077–7.093)	0.035 *
ECOG (0–2 vs >2)	2.927 (1.112–7.706)	0.030 *	2.756 (1.020–7.448)	0.046 *
IPI (0–2 vs 3–5)	2.773 (1.072–7.173)	0.035 *	2.910 (1.099–7.709)	0.032 *
Stage (I-II vs III-IV)	1.896 (0.711–5.052)	0.201
LDH (normal vs high)	1.004 (0.408–2.472)	0.994
BM (+ vs -)	1.814 (0.653–5.043)	0.254
GCB (yes vs no)	2.094 (0.645–6.805)	0.219
Age (< 60 vs ≥ 60)	1.010 (0.410–2.487)	0.982

Only factors identified as significant in the univariate analysis were included in the multivariate analysis. HR, hazard ratio; 95% IC, 95% confidence interval of hazard ratio; ECOG, Eastern Cooperative Group; LDH, lactate dehydrogenase; IPI, International Prognostic Index; BM, bone marrow; GCB, germinal center B-cell like.

*P ≤ 0.05