Table 3. Multivariate COX regression analysis for overall survival in DLBCL patients including prognostic clinical variables and both CXCR4 and CXCR7 expression.
| Multivariate COX Regression | ||
|---|---|---|
| HR (IC 95%) | P | |
| CXCR4 (+ vs -) | 3.401 (1.188–9.733) | 0.023 * |
| CXCR7 (+ vs -) | 2.605 (1.001–6.782) | 0.050 * |
| ECOG (0–2 vs >2) | 2.828 (0.996–8.029) | 0.051 |
| IPI (0–2 vs 3–5) | 3.029 (1.106–8.299) | 0.031 * |
All the variables included in this analysis were significant factors in the univariate analysis. HR, hazard ratio; 95% IC, 95% confidence interval of hazard ratio; ECOG, Eastern Cooperative Group; IPI, International Prognostic Index.
*P ≤ 0.05