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. 2018 Jun 19;13(6):e0198618. doi: 10.1371/journal.pone.0198618

Table 2. Use of prescribed and non-prescribed medications by trimester of pregnancy and by pharmacological class according to ATC code level 1 of the study population.

Trimester of pregnancy Overall
(Total n = 558)
Prescribed
(Total n = 300)
Non-prescribed
(Total n = 258)
N % n % n %
1st 133 23.8 88 29.3 45 17.4
2nd 225 40.3 104 34.7 121 46.9
3rd 79 14.2 36 12 43 16.7
All 54 9.7 52 17.3 2 0.8
Unknown 67 12 20 6.7 47 18.2
ATC class* Overall
(Total n = 558)
Prescribed
(Total n = 300)
Non-prescribed
(Total n = 258)
N % n % n %
A 89 16 41 13.7 48 18.6
B 40 7.2 40 13.3 - -
C 21 4 22 7.3 1 0.4
G 44 7.9 44 14.7 - -
H 43 7.7 43 14.4 - -
J 71 12.8 66 22 5 1.9
M 20 3.5 4 1.3 16 6.2
N 207 37.1 27 8.9 180 69.8
R 20 3.6 12 4.1 8 3.1
V 1 0.2 1 0.3 - -

* ATC class A: Alimentary tract and metabolism–B: Blood and blood forming organs–C: Cardiovascular system–G: Genitourinary system and reproductive hormones–H: Systemic hormonal preparations (excluding reproductive hormones and insulin)–J: Anti-infective for systemic use–M: Musculoskeletal system–N: Nervous system–R: Respiratory system–V: Various ATC structures