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. 2018 Jun 19;13(6):e0198618. doi: 10.1371/journal.pone.0198618

Table 3. Results of the multivariate logistic regression analysis identifying the variables significantly associated with the different outcomes of interest.

Variable OR (95% CI) p value
Model 1. Knowledge that a pregnant woman with a chronic health condition must discuss whether or not to take a medication with the physician
Log likelihood = -208.13, χ2 = 152.18 (18 df), p<0.0001
Need of additional information about using medications in pregnancy 2.59 (1.55–4.34) <0.001
Self-perceived health status 1.33 (1.34–1.55) <0.001
At least one health problem in the last year 4.88 (1.75–13.59) 0.002
Age (years)
    ≤20 1*
    31–35 2.92 (1.18–7.23) 0.02
    36–40 3.5 (1.27–9.69) 0.016
History of abortion 0.57 (0.34–0.95) 0.031
Employment status 1.79 (1.05–3.05) 0.032
Nationality 1.88 (1.01–3.5) 0.044
Correct knowledge how to use medications according to the trimester of pregnancy 1.95 (1.01–3.76) 0.045
Model 2. Knowledge of the potential risk of using non-prescribed medications and the need to receive a medical advice during pregnancy
Log likelihood = -193.6, χ2 = 69.8 (8 df), p<0.0001
Employment status 2.54 (1.42–4.55) 0.002
Correct knowledge of the possible damages to the women due to the use of medications in pregnancy 2.44 (1.35–4.44) 0.003
Physicians as a source of information about using medications in pregnancy 2.72 (1.37–5.39) 0.004
Correct knowledge how to use medications according to the trimester of pregnancy 2.49 (1.2–5.19) 0.015
Physicians as a source of information on the risk for the unborn baby due to the use of medications in pregnancy 1.82 (1.04–3.17) 0.036
Model 3. Had used at least one medication
Log likelihood = -257.1, χ2 = 164.28 (17 df), p<0.0001
Gestational age (trimester)
    Second 1*
    Third 2.36 (1.51–3.69) <0.001
High-risk pregnancy 6.03 (2.77–13.1) <0.001
Correct knowledge that a pregnant woman with a chronic health condition must discuss whether or not to take a medication with the physician 2.53 (1.49–4.3) 0.001
Age (years)
    ≤20 1*
    26–30 2.27 (1.26–4.1) 0.006
    31–35 2.75 (1.44–5.26) 0.002
At least one health problem in the last year 2.81 (1.41–5.58) 0.003
Educational level
    College degree or higher 1*
    No formal education or elementary school 3.53 (1.25–9.97) 0.017
    Middle school 2.53 (1.09–5.85) 0.03
    High school 2.99 (1.39–6.43) 0.005
Nationality 2.25 (1.24–4.09) 0.007
Model 4. Had practiced at least one self-medication
Log likelihood = -287.43, χ2 = 115.02 (13 df), p<0.0001
Correct knowledge about the potential risk of using non-prescribed medications in pregnancy 0.34 (0.19–0.61) <0.001
At least one medication with prescription in the current pregnancy 2.45 (1.62–3.7) <0.001
Parity 2.01 (1.29–3.14) 0.002
Nationality 2.19 (1.25–3.83) 0.006
Correct knowledge that a pregnant woman with a chronic health condition must discuss whether or not to take a medication with the physician 2.05 (1.19–3.52) 0.009
Age (years)
    ≤20 1*
    >40 14.68 (1.42–151.68) 0.024
History of abortion 0.63 (0.41–0.96) 0.032
Employment status 1.55 (1.02–2.37) 0.04
Need of additional information about using medications in pregnancy 1.52 (1.01–2.31) 0.049

* Reference category