Skip to main content
. 2018 Jun 8;9(44):27471–27486. doi: 10.18632/oncotarget.25463

Table 1. Candidates for prognostic markers based on somatic mutations in PCNSL.

Symbol Refseq Description Alias HR P-value
KMT2A NM_005933 Homo sapiens lysine methyltransferase 2A (KMT2A), transcript variant 2 KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1, MLL1A, TET1-MLL, TRX1, WDSTS, MLL-AF9, lysine methyltransferase 2A, Histone-lysine N-methyltransferase HRX 4.44E+12 <0.0011
AR NM_001011645 Homo sapiens androgen receptor (AR), transcript variant 2 AR, AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4 (nuclear receptor subfamily 3, group C, member 4), SBMA, SMAX1, TFM, androgen receptor 1.79E+10 0.0011
MYC NM_002467 Homo sapiens MYC proto-oncogene, bHLH transcription factor (MYC), transcript variant 1 MYC, MRTL, MYCC, bHLHe39, c-Myc, v-myc avian myelocytomatosis viral oncogene homolog, MYC proto-oncogene, bHLH transcription factor 3.05E-01 0.0012
NSD1 NM_172349 Homo sapiens nuclear receptor binding SET domain protein 1 (NSD1), transcript variant 1 STO 2.82E+10 0.0015
EPHA3 NM_005233 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1 EPHA3, Epha3, AW492086, Cek4, ETK1, End3, Hek, Hek4, Mek4, Tyro4, EK4, ETK, EPH receptor A3, HEK, HEK4, TYRO4 3.54E+11 0.0033
MYH11 NM_001040114 Homo sapiens myosin heavy chain 11 (MYH11), transcript variant SM1B MYH11, AAT4, FAA4, SMHC, SMMHC, myosin, heavy chain 11, smooth muscle, myosin heavy chain 11 11.94 0.0043
MARK1 NM_001286124 Homo sapiens microtubule affinity regulating kinase 1 (MARK1), transcript variant 1 MARK1, MARK, Par-1c, Par1c, microtubule affinity regulating kinase 1 1.48E-10 0.0099
NTRK1 NM_002529 Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 2 NTRK1, MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, neurotrophic receptor tyrosine kinase 1 1.06E+10 0.0193
FOXO1 NM_002015 Homo sapiens forkhead box O1 (FOXO1) FOXO1, FKH1, FKHR, FOXO1A, forkhead box O1 0.15 0.0278
PAX5 NM_001280547 Homo sapiens paired box 5 (PAX5), transcript variant 2 PAX5, ALL3, BSAP, paired box 5 0.05 0.0307
RUNX1 NM_001001890 Homo sapiens runt related transcription factor 1 (RUNX1), transcript variant 2 RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, runt related transcription factor 1 5.55E-10 0.0395
UBR5 NM_001282873 Homo sapiens ubiquitin protein ligase E3 component n-recognin 5 (UBR5), transcript variant 2 UBR5, DD5, EDD, EDD1, HYD, ubiquitin protein ligase E3 component n-recognin 5 3.25E+01 0.0413