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. 2018 May 7;26:e20170561. doi: 10.1590/1678-7757-2017-0561

Table 3. Proteins of the saliva identified in the pool analysis.

Accession number Protein name score Cover(%)
P16885 1-phosphatidylinositol 4_5-bisphosphate phosphodiesterase gamma-2 314.78 4.51
P68032 Actin_ alpha cardiac muscle 1 6085.31 31.30
P68133 Actin_ alpha skeletal muscle 6085.31 31.30
P62736 Actin_ aortic smooth muscle 4676.94 28.38
P60709 Actin_ cytoplasmic 1 17496 67.20
P63261 Actin_ cytoplasmic 2 17496 67.20
P63267 Actin_ gamma-enteric smooth muscle 4676.94 28.46
Q01518 Adenylyl cyclase-associated protein 1 440.27 26.11
C9JKR2 Albumin_ isoform CRA_k 26466.72 74.82
P01009 Alpha-1-antitrypsin 2252.60 22.97
P01023 Alpha-2-macroglobulin 665.70 22.86
P04745 Alpha-amylase 1 153591.90 78.86
P19961 Alpha-amylase 2B 110753.50 58.51
P06733 Alpha-enolase 1637.76 33.87
Q01484 Ankyrin-2 52.62 2.75
P03973 Antileukoproteinase 701.53 28.03
P63010 AP-2 complex subunit beta 338.39 2.35
P02647 Apolipoprotein A-I 612.31 39.70
P02652 Apolipoprotein A-II 886.78 69.00
Q5FYB0 Arylsulfatase J 389.18 10.35
Q8IYB8 ATP-dependent RNA helicase SUPV3L1_ mitochondrial 235.17 6.23
P04280 Basic salivary proline-rich protein 1 3925.20 58.67
P02812 Basic salivary proline-rich protein 2 73554.97 69.47
P61769 Beta-2-microglobulin 3725.17 48.74
Q562R1 Beta-actin-like protein 2 1532.83 13.30
P13929 Beta-enolase 264.78 13.36
Q96DR5 BPI fold-containing family A member 2 4561.18 58.23
Q8N4F0 BPI fold-containing family B member 2 6508.75 30.79
A0A087WXK1 BRCA1-A complex subunit Abraxas (Fragment) 332.77 16.93
Q8N4G4 CA6 protein 419.28 4.47
O75638 Cancer/testis antigen 2 716.39 19.05
P23280 Carbonic anhydrase 6 15792.21 62.01
P00450 Ceruloplasmin 71.04 8.45
E9PM92 Chromosome 11 open reading frame 58 258.69 15.29
P01024 Complement C3 833.42 21.17
P51160 Cone cGMP-specific 3'_5'-cyclic phosphodiesterase subunit alpha' 232.14 11.07
H3BRY3 Coronin 502.10 22.11
P31146 Coronin-1A 502.10 24.95
Q92772 Cyclin-dependent kinase-like 2 457.97 11.97
P04080 Cystatin-B 2288.27 45.92
P01034 Cystatin-C 3131.85 51.37
P28325 Cystatin-D 3348.32 61.97
P01036 Cystatin-S 34860.66 73.76
P09228 Cystatin-SA 24277.69 67.38
P01037 Cystatin-SN 23133.23 70.21
P54108 Cysteine-rich secretory protein 3 284.38 21.63
P32320 Cytidine deaminase 1245.08 66.44
Q9UGM3 Deleted in malignant brain tumors 1 protein 306.82 4.97
Q13609 Deoxyribonuclease gamma 411.37 15.74
A0A0A0MT68 Deoxyribonuclease 411.37 16.67
P27487 Dipeptidyl peptidase 4 73.31 4.83
O60216 Double-strand-break repair protein rad21 homolog 322.95 19.02
R4GN68 Dual-specificity mitogen-activated protein kinase kinase 4 780.16 97.56
V9HW75 Epididymis secretory protein Li 109 954.67 25.48
B1AK53 Espin 277.28 4.80
Q01469 Fatty acid-binding protein_ epidermal 475.76 30.37
Q8NCQ5 F-box only protein 15 465.73 3.73
P02679 Fibrinogen gamma chain 372.17 21.63
Q08380 Galectin-3-binding protein 237.96 18.97
P06744 Glucose-6-phosphate isomerase 222.14 22.04
E7ETY7 Glutathione peroxidase 341.42 22.78
P09211 Glutathione S-transferase P 519.29 25.71
P04406 Glyceraldehyde-3-phosphate dehydrogenase 407.39 11.64
Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 718.24 4.81
P00738 Haptoglobin 960.32 41.87
G3V1N2 HCG1745306_ isoform CRA_a 11936.33 57.27
P69905 Hemoglobin subunit alpha 13598.42 54.93
P68871 Hemoglobin subunit beta 18402.54 89.80
P02042 Hemoglobin subunit delta 5838.89 63.95
P02100 Hemoglobin subunit epsilon 3895.00 6.80
P69891 Hemoglobin subunit gamma-1 3895.00 6.80
P69892 Hemoglobin subunit gamma-2 3895.00 6.80
P15515 Histatin-1 16204.54 36.84
P15516 Histatin-3 2631.50 13.73
Q16695 Histone H3.1t 524.06 23.53
Q05469 Hormone-sensitive lipase 43.68 5.30
Q4G0P3 Hydrocephalus-inducing protein homolog 15.21 1.93
A0A0G2JMB2 Ig alpha-2 chain C region (Fragment) 43004.29 79.12
A0A0A0MS07 Ig gamma-1 chain C region (Fragment) 2528.80 42.37
A0A087WYJ9 Ig mu chain C region 4012.85 48.67
P04220 Ig mu heavy chain disease protein 3190.64 37.85
P01876 Immunoglobulin heavy constant alpha 1 38140.46 73.65
P01877 Immunoglobulin heavy constant alpha 2 32255.84 65.29
P01857 Immunoglobulin heavy constant gamma 1 4336.06 47.88
P01859 Immunoglobulin heavy constant gamma 2 1181.17 37.42
P01860 Immunoglobulin heavy constant gamma 3 1276.14 14.59
P01861 Immunoglobulin heavy constant gamma 4 1489.84 38.23
P01871 Immunoglobulin heavy constant mu 4017.99 50.33
A0A075B7F0 Immunoglobulin heavy variable 3/OR16-10 (non-functional) (Fragment) 299.80 9.48
A0A075B7B8 Immunoglobulin heavy variable 3/OR16-12 (non-functional) (Fragment) 242.49 9.40
A0A075B7E8 Immunoglobulin heavy variable 3/OR16-13 (non-functional) (Fragment) 242.49 9.40
S4R460 Immunoglobulin heavy variable 3/OR16-9 (non-functional) 5489.71 31.25
P01762 Immunoglobulin heavy variable 3-11 299.80 9.40
P01766 Immunoglobulin heavy variable 3-13 299.80 9.48
A0A0C4DH32 Immunoglobulin heavy variable 3-20 (Fragment) 299.80 9.40
A0A0B4J1V1 Immunoglobulin heavy variable 3-21 299.80 9.40
P01764 Immunoglobulin heavy variable 3-23 242.49 12.82
P01768 Immunoglobulin heavy variable 3-30 242.49 31.62
P01772 Immunoglobulin heavy variable 3-33 242.49 31.62
A0A0B4J1X8 Immunoglobulin heavy variable 3-43 299.80 9.32
P01763 Immunoglobulin heavy variable 3-48 299.80 9.40
P01767 Immunoglobulin heavy variable 3-53 242.49 12.93
A0A0C4DH42 Immunoglobulin heavy variable 3-66 242.49 12.93
P01780 Immunoglobulin heavy variable 3-7 299.80 9.40
A0A0B4J1X5 Immunoglobulin heavy variable 3-74 242.49 9.40
P01782 Immunoglobulin heavy variable 3-9 299.80 9.32
P01591 Immunoglobulin J chain 20006.96 49.06
P01834 Immunoglobulin kappa constant 28856.88 82.24
A0A0C4DH90 Immunoglobulin kappa variable 3/OR2-268 (non-functional) (Fragment) 362.90 7.76
P04433 Immunoglobulin kappa variable 3-11 1198.54 26.09
P01624 Immunoglobulin kappa variable 3-15 362.90 7.83
A0A075B6H7 Immunoglobulin kappa variable 3-7 (non-functional) (Fragment) 362.90 7.76
A0A0A0MRZ8 Immunoglobulin kappa variable 3D-11 1198.54 26.09
A0A0C4DH55 Immunoglobulin kappa variable 3D-7 362.90 7.56
P06312 Immunoglobulin kappa variable 4-1 250.98 19.83
P0CG04 Immunoglobulin lambda constant 1 40610.55 77.36
P0DOY2 Immunoglobulin lambda constant 2 44714.51 93.40
P0DOY3 Immunoglobulin lambda constant 3 44714.51 93.40
P0CF74 Immunoglobulin lambda constant 6 23147.62 50.94
A0M8Q6 Immunoglobulin lambda constant 7 19435.36 36.79
P01715 Immunoglobulin lambda variable 3-1 344.58 38.26
B9A064 Immunoglobulin lambda-like polypeptide 5 40610.55 38.32
Q9BQU0 Inhibitory NK receptor 242.62 11.21
Q9NVH2 Integrator complex subunit 7 267.39 4.26
Q01638 Interleukin-1 receptor-like 1 304.24 7.01
H0YNL8 Iron-responsive element-binding protein 2 377.91 29.09
A0A0G2JPA6 Killer cell immunoglobulin-like receptor 3DL2 242.62 11.64
P22079 Lactoperoxidase 2259.91 35.11
P02788 Lactotransferrin 862.74 28.59
A6NMS7 Leucine-rich repeat-containing protein 37A 263.12 1.71
A6NM11 Leucine-rich repeat-containing protein 37A2 252.18 1.71
O60309 Leucine-rich repeat-containing protein 37A3 276.06 4.53
P31025 Lipocalin-1 14925.97 53.98
Q86W92 Liprin-beta-1 292.75 10.29
P00338 L-lactate dehydrogenase A chain 196.57 21.69
Q9BY66 Lysine-specific demethylase 5D 307.10 8.58
P61626 Lysozyme C 15283.53 66.89
P14174 Macrophage migration inhibitory factor 616.56 47.83
C9JF79 Malate dehydrogenase (Fragment) 263.72 11.71
P40925 Malate dehydrogenase_ cytoplasmic 653.55 11.38
Q5HYA8 Meckelin 241.84 1.61
Q9Y4B5 Microtubule cross-linking factor 1 26.23 1.52
Q8TAX7 Mucin-7 13700.40 9.28
U3KPS2 Myeloblastin 554.69 17.67
P24158 Myeloblastin 631.43 28.52
Q9NYA4 Myotubularin-related protein 4 315.44 7.11
P59665 Neutrophil defensin 1 1789.52 25.53
P59666 Neutrophil defensin 3 1789.52 25.53
Q9BYH8 NF-kappa-B inhibitor zeta 371.15 4.32
Q2L696 Nucb2 splice variant 663.95 25.13
A0A087WSV8 Nucleobindin 2_ isoform CRA_b 954.67 25.48
P80303 Nucleobindin-2 954.67 25.48
P04746 Pancreatic alpha-amylase 88276.59 55.97
P42338 Phosphatidylinositol 4_5-bisphosphate 3-kinase catalytic subunit beta isoform 561.79 6.26
A0A0A0MRF9 Phosphoinositide phospholipase C 313.90 4.55
P13796 Plastin-2 283.93 25.04
Q86YL7 Podoplanin 866.94 34.57
P11940 Polyadenylate-binding protein 1 582.59 10.69
E7ERJ7 Polyadenylate-binding protein 582.59 11.26
Q8NDX5 Polyhomeotic-like protein 3 348.42 3.05
P01833 Polymeric immunoglobulin receptor 12791.93 57.98
Q8TCS8 Polyribonucleotide nucleotidyltransferase 1_ mitochondrial 32.49 3.19
Q6S8J3 POTE ankyrin domain family member E 4118.47 13.86
A5A3E0 POTE ankyrin domain family member F 4040.70 11.72
P0CG38 POTE ankyrin domain family member I 3413.22 4.74
P0CG39 POTE ankyrin domain family member J 2796.68 3.85
Q8TED1 Probable glutathione peroxidase 8 341.42 17.22
Q8IZM9 Probable sodium-coupled neutral amino acid transporter 6 426.92 6.80
K7EJ44 Profilin 470.78 37.50
P07737 Profilin-1 910.82 49.29
P12273 Prolactin-inducible protein 30448.27 76.71
A0A0A0MT31 Proline-rich protein 4 23475.68 72.29
P07602 Prosaposin 510.46 39.12
Q5W0V3 Protein FAM160B1 862.81 23.66
Q6P5S2 Protein LEG1 homolog 6592.09 36.97
Q9H7Z3 Protein NRDE2 homolog 45.79 1.20
P05109 Protein S100-A8 3184.30 23.66
P06702 Protein S100-A9 1737.55 77.19
O14795 Protein unc-13 homolog B 59.05 1.19
H3BQ60 Puratrophin-1 (Fragment) 266.79 50.00
Q9BYX7 Putative beta-actin-like protein 3 2063.16 10.67
Q5VSP4 Putative lipocalin 1-like protein 1 3097.31 11.11
P52566 Rho GDP-dissociation inhibitor 2 1026.87 30.35
P35913 Rod cGMP-specific 3'_5'-cyclic phosphodiesterase subunit beta 374.14 8.08
P02810 Salivary acidic proline-rich phosphoprotein 1/2 4566.91 72.29
P02787 Serotransferrin 4566.92 48.42
P02768 Serum albumin 63281.61 75.04
O00193 Small acidic protein 258.69 13.11
P02808 Statherin 41653.6 48.39
P02814 Submaxillary gland androgen-regulated protein 3B 20898.6 65.82
Q9UH99 SUN domain-containing protein 2 70.82 1.67
A0A075B6V5 T cell receptor alpha variable 36/delta variable 7 (Fragment) 278.89 24.78
Q7Z6L1 Tectonin beta-propeller repeat-containing protein 1 384.23 7.12
F2Z350 Testis-expressed protein 29 447.37 32.14
Q7Z4L5 Tetratricopeptide repeat protein 21B 78.57 4.56
P20061 Transcobalamin-1 378.51 22.86
P29401 Transketolase 676.10 30.98
Q6ZMR5 Transmembrane protease serine 11A 281.15 11.16
P02766 Transthyretin 438.46 44.22
P60174 Triosephosphate isomerase 651.56 36.36
O43818 U3 small nucleolar RNA-interacting protein 2 297.84 16.00
A0A0J9YY99 Uncharacterized protein (Fragment) 242.49 12.82
H7C2Y3 Uncharacterized protein C2orf80 (Fragment) 318.87 16.41
H0Y8H3 Uncharacterized protein C3orf67 (Fragment) 590.54 74.68
A0A087WZY1 Uncharacterized protein 22581.8 16.60
A0A0G2JMZ2 Uncharacterized protein 252.18 1.71
A0A0G2JRT3 Uncharacterized protein 252.18 1.77
P02774 Vitamin D-binding protein 245.21 21.52
Q14508 WAP four-disulfide core domain protein 2 935.99 33.87
Q9UDV6 Zinc finger protein 212 424.39 16.97
P25311 Zinc-alpha-2-glycoprotein 2292.60 31.54
Q96DA0 Zymogen granule protein 16 homolog B 46355.09 58.17