| SP1 |
11 |
AR, Dmd, Foxo3, Hdac2, Hdac3, Hdac4, Hif1a, Kdm5a, Mef2c, Myh7, MylK, NFkB1, Rb1, Rxra, Tp53, Vegf, Vegfa |
| HIF1A |
10 |
AR, Acta1, Acta2, Arnt2, Cnntb1, Epas1, Foxo3, Hdac2, Hdac3, Hdac4, Hdac5, Hdac7, Mef2c, Mstn, Myc, Myh1, Myh2, Myh3, Myh4, Myh6, Myl1, MylK2,NFkB (complex), Ppargc1a, Rb1, Rxra, Sp1, Tp53, Ttn, Ucp3, Vegf, Vegfa
|
| SMARCA4 |
9 |
Acta1, Acta2, Actb, Actl6a, Actn4, AR, Ctnnb1, Dysf, Gli1, Hdac2, Hdac4, Mef2c, Myc, Myh3, Myh7, Myh11, Myl1, Myl4, Myl5, MylK, Mylpf, MyoD1, MyoG, NFkB (complex), Pparg, Rb1, Rxra, Six1, Sp1, Tp53, Tpm1
|
| TCF7L2 |
9 |
AR, Ctnnb1, Epas1, Hdac2, Myc, MylK2, Myo6, Ppargc1a, Tp53 |
| ARNT2 |
8 |
Epas1, Gli1, Hif1a, Myh6, Myh7, Vegfa |
| CTNNB1 |
8 |
Acta2, Actb, Actc1, Actn4, AR, Epas1, Foxo3, Gli1, Hdac2, Hdac3, Hdac4, Hdac5, Hdac7, Myc, Myf5, Myh3, Myh6, Myl4, MylK, MyoD1, MyoG, NFkB (complex), Rxra, Six1, Sp1, Stat5b, Smarca4, Tcf7l2, Tnnc1, Tp53, Vegfa
|
| STAT4 |
8 |
Myc, NFkB (complex), Smarca4, Vegfa |
| MYC |
7 |
Acta1, Actb, Actn1, Actn4, Aimp2, AR, Ctnnb1, Egr2, Epas1, Foxo3, Gli1, Hdac2, Hdac3, Hdac5, Hif1a, Kdm5a, Myh7, Myl9, Mylpf, Myo1B, Myo1C, NFkB (complex), Rb1, Smarca4, Sp1, Stat4, Stat5b, Tcf7l2, Tnni3, Tnnt3, Tp53, Tpm1, Vegf, Vegfa
|
| TP53 |
7 |
Acta2, Actb, Actn1, Actn4, Aimp2, AR, Ctnnb1, Egr2, Epas1, Foxo3, Gli1, Hdac2, Hdac3, Hdac5, Hif1a, Myc, Myh9, Myh10, Myh16, Myl4, Myl9, MylK, Myo1c, Myo6, Myo10, MyoD1, Myof, NFkB (complex), Ppargc1a, Rb1, Smarca4, Sp1, Tcf7l2, Tp53, Tpm1, Tpm2, Tpm4, Ucp3, Vegf, Vegfa
|
| FOXO3 |
6 |
AR, Ctnnb1, Egr2, Hdac2, Hif1a, Mef2c, Mstn, Myc, Myo6, MyoC, MyoD1, NFkB (complex), Ppargc1a, Rb1, Sp1, Tp53, Ucp2, Vegfa |
| EGR2 |
6 |
Foxo3, Mef2c, Myc, MyoC, Ucp3, Vegfa |
| NFkB (complex) |
6 |
Actb, AR, Ctnn1b, Epas1, Hdac2, Hdac3, Hdac4, Hdac5, Hif1a, Mstn, Myc, MylK, MylK3, Myo1E, MyoD1, Stat4, Tp53, Vegfa |
| RB1 |
6 |
Actb, Actc1, Actn2, Actn3, AR, Foxo3, Hdac2, Hdac3, Hif1a, Kdm5a, Mef2c, Myc, Mstn, Myh2, Myh4, Myh6, Myh7, Myh8, Myl1, Myl4, Myl6B, MyoD1, MyoM2, NFkB2, PPargc1a, Ryr1, Smarca4, Sp1, Tnnc1, Tnnc2, Tnni2, Tnnt1, Tp53, Tpm1, Tpm2, Vegfa |
| GLI1 |
6 |
Arnt2, AR, Ctnnb1, Hdac2, Myc, Mef2c, Rxra, Smarca4, Tp53, Vegfa |
| MEF2C |
6 |
Acta1, Actc1, Actn2, AR, Dmd, Egr2, Epas1, Foxo3, Gli1, Hdac3, Hdac4, Hdac5, Hdac7, Hif1a, Mstn, Myh1, Myh6, Myh7, Myl2, Myl4, Myl7, MylK2, Mylpf, MyoD1, MyoG, MyoM1, MyoM2, MyoT, MyoZ1, MyoZ2, Smarca4, Ppargc1a, Rb1, Sp1, Tnnc1, Tnni2, Tnnt2, Tpm1, Ttn, Vegfa |
| STAT5B |
5 |
Actc1, AR, Ctnnb1, Myc, Myh1, Myh6, Myh7, Myl1, Myl2, Myl4, Myl7, NFkB (complex), Pparg, Rxra, Tp53, Tnnc1, Tnni1, Tnnt1, Tpm3
|
| PPARGC1A |
5 |
AR, Dmd, Epas1, Foxo3, Hdac5, Hif1a, Mef2c, Mstn, Myh6, Myh7, Myl2, MyoD1, MyoG, NFkB (complex), Rxra, Rb1, Tcf7l2, Tnni1, Tp53, Ucp2, Ucp3, Vegfa
|
| MYOD1 |
5 |
Acta1, Actc1, AR, Ctnnb1, Dmd, Dysf, Foxo3, Hdac3, Hdac4, Hdac5, Mef2c, Mstn, Myf5, Myf6, Myh2, Myh3, Myh7, Myl1, Myl4, Mylpf, Myo5b, NFkB1, Ppargc1a, Rb1, Rxra, Ryr1, Six1, Smarca4, Sp1, Tnnc1, Tnnc2, Tnni1, Tnni2, Tnnt1, Tnnt2, Tnnt3, Tp53, Tpm2, Ttn, Ucp3 |
| EPAS1 |
5 |
AR, Arnt2, Ctnnb1, Hif1a, Mef2c, Myc, Myh4, Myo7a, MyoM2, NFkB (complex), Ppargc1a, Smarca4, Sp1, Tcf7l2, Tnni1, Tp53, Ucp2, Vegf, Vegfa |
| Inhibited TF |
Top 25 TFs |
Interacts with functionally significant muscle genes: |
| KDM5A |
8 |
Actc1, Actn2, Actn3, AR, Hdac2, Myc, Myh2, Myh4, Myh6, Myh7, Myh8, Myl1, Myl4, Myl6b, MyoM2, Rb1, Ryr1, Sp1, Tnnc1, Tnnc2, Tnni2, Tnnt1, Tnnt2, Tpm1, Tpm2, Vegf |
