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. 2018 Feb 8;314(5):G597–G609. doi: 10.1152/ajpgi.00310.2017

Fig. 1.

Fig. 1.

Expression of organic solute transporter (OST) α/β in human control livers and patients with nonalcoholic steatohepatitis (NASH) and primary biliary cholangitis (PBC). A: quantitative RT-PCR analysis of mRNA levels of OSTα and OSTβ in liver samples of NASH and PBC patients and controls. B and C: Western blots for OSTα and OSTβ proteins and corresponding densitometry. Values are means ± SD. ****P = 0.0001; ***P = 0.0007; **P < 0.005; *P = 0.0218. D: representative immunofluorescence of OSTα (red) and OSTβ (green) proteins in liver samples of NASH and PBC patients. Nuclei of cells in liver samples were stained with 4′,6-diaminido-2-phenylindole (DAPI, blue). Scale bars = 100 μm. Insets: colocalization of OSTα and OSTβ on parenchymal membrane.