Fig. 3.
Mathematical modeling of microbubble dissolution time [time to dissolution (TDiss) vs. initial bubble radius] for the following atmospheric pressures: sea level (Eugene, OR), 1,668 m (Aurora, CO), and 5,260 m (Mt. Chacaltaya, Bolivia). Calculated using the Solano-Altamirano and Goldman (67) equation (Eq. 1). Initial radii (Ro) range from 5 to 25 µm; diffusion constant, D = 2,900 (μm2/s); undersaturation factor (f) = 0.917, 0.879, and 0.873 for sea level, 1,668 m, and 5,260 m, respectively; surface tension for venous blood (γ) = 0.5 atm μm. *P < 0.05 for 5,260 m compared with sea level.