Skip to main content
. 2017 Dec 14;124(5):1363–1376. doi: 10.1152/japplphysiol.00474.2017

Table 4.

Metabolic and hematological data for normobaric hypoxia vs. hypobaric hypoxia

Normobaric Hypoxia
Hypobaric Hypoxia
Rest 70 W 100 W 130 W Rest 70 W 100 W 130 W
AaDO2, mmHg 2.28 ± 1.99 14.6 ± 4.03 16.9 ± 4.26 20.9 ± 4.44 1.75 ± 2.37 11.1 ± 3.42 15.0 ± 4.83 17.0 ± 5.48
VE, l/min 17.8 ± 3.8 51.5 ± 5.0 69.6 ± 6.4 101.3 ± 20.3 15.0 ± 3.5 46.3 ± 12.1 65.9 ± 21.3 82.1 ± 28.1
VA, l/min 11.5 ± 3.7 41.7 ± 3.4 57.7 ± 5.1 87.9 ± 17.7 9.64 ± 2.6 37.1 ± 9.5 55.0 ± 17.6 71.0 ± 24.0
VD/VT 0.41 ± 0.09 0.24 ± 0.07 0.23 ± 0.07 0.15 ± 0.05 0.38 ± 0.09 0.25 ± 0.06 0.23 ± 0.07 0.23 ± 0.08
o2, l/min 0.38 ± 0.08 1.30 ± 0.17 1.62 ± 0.21 2.06 ± 0.36 0.37 ± 0.09 1.19 ± 0.26 1.53 ± 0.36 1.77 ± 0.44
co2, l/min 0.36 ± 0.08 1.26 ± 0.12 1.66 ± 0.15 2.24 ± 0.27 0.30 ± 0.07 1.11 ± 0.26 1.51 ± 0.40 1.77 ± 0.49
RER 0.94 ± 0.06 0.98 ± 0.05 1.03 ± 0.08 1.10 ± 0.08 0.83 ± 0.08 0.93 ± 0.08 0.98 ± 0.10 0.99 ± 0.07
PAO2 45.7 ± 4.7 49.6 ± 3.5 52.2 ± 3.3 55.8 ± 5.4 43.4 ± 2.4 47.8 ± 4.2 50.5 ± 5.6 52.7 ± 6.5
PaO2 43.5 ± 5.9 35.0 ± 4.1 35.3 ± 3.8 35.0 ± 5.5 41.6 ± 1.6 36.6 ± 3.3 35.4 ± 3.5 35.7 ± 2.6
PaCO2 27.4 ± 3.4 26.2 ± 2.7 25.0 ± 3.3 22.7 ± 5.1 27.5 ± 2.2 26.3 ± 2.8 24.6 ± 4.1 22.9 ± 5.5
HR, beats/min 102 ± 23 143 ± 18 157 ± 18 160 ± 22 82 ± 21 128 ± 24 144 ± 26 156 ± 21
SV, ml 64 ± 11 82 ± 20 96 ± 17 86 ± 15 65 ± 11 88 ± 20 85 ± 17 92 ± 15
QT, l/min 6.4 ± 1.4 11.7 ± 2.0 14.9 ± 2.1 13.5 ± 2.0 5.2 ± 1.1 11.3 ± 3.3 12.3 ± 3.2 13.6 ± 2.5
PASP, mmHg 31.7 ± 7.2 44.2 ± 10.7 49.8 ± 9.0 50.0 ± 11.5 31.2 ± 6.7 39.6 ± 7.6 44.5 ± 7.1 42.8 ± 8.5
TPR, mmHg·l−1·min−1 5.08 3.90 3.35 3.71 6.22 3.77 3.88 3.19
TPR (HCT), mmHg·l−1·min−1 5.64 4.34 3.53 3.26 6.91 4.19 4.08 3.36
SaO2 77.7 ± 7.2 65.7 ± 7.5 66.3 ± 6.9 65.6 ± 8.2 76.3 ± 2.1 68.6 ± 5.4 66.6 ± 5.8 67.3 ± 3.9
CaO2, ml O2/dl 15.0 ± 2.1 13.3 ± 1.1 13.5 ± 1.4 13.6 ± 1.4 14.9 ± 2.5 13.5 ± 1.6 12.5 ± 1.0 13.1 ± 1.1
pH 7.50 ± 0.05 7.49 ± 0.03 7.47 ± 0.04 7.43 ± 0.06 7.50 ± 0.03 7.48 ± 0.03 7.46 ± 0.04 7.42 ± 0.07
HCT, % 41.1 ± 4.8 40.6 ± 5.3 42.1 ± 3.9 44.4 ± 2.9 42.3 ± 4.2 42.1 ± 6.2 44.3 ± 4.6 43.3 ± 6.2
tHb, g/dl 13.2 ± 1.5 13.4 ± 1.6 13.9 ± 1.5 14.3 ± 1.1 13.2 ± 2.0 13.3 ± 1.5 12.9 ± 1.6 13.6 ± 1.6
Core temp, °C 37.1 ± 0.4 36.9 ± 0.8 36.9 ± 0.9 36.7 ± 1.1 37.2 ± 0.3 36.9 ± 0.6 36.9 ± 0.7 36.9 ± 0.8
Lactate, mmol/l 1.84 ± 0.69 3.34 ± 0.78 5.23 ± 1.26 7.88 ± 2.26 1.74 ± 0.88 3.59 ± 1.53 6.11 ± 3.08 8.48 ± 4.81
n 7 7 7 5 7 7 7 6

Values are means ± SD.

P < 0.05 rest vs. exercise.