Fig. 4.
Increase in profibrotic gene expression in kidney compared with SS rats. Real-time PCR assessment of gene expression levels in kidneys of Resp18mutant and SS rats. mRNA obtained from kidney were converted to cDNA and quantified with gene-specific primers. Gapdh was used as internal control. Values are fold change in SS (n = 5–6), Resp18mutant (n = 6); data are means ± SE. Bars labeled with different letters are significantly different from each other; levels of statistical significance were analyzed by one-way ANOVA. LS, low salt; HS, high salt. *P ≤ 0.05.