Fig. 6.

Mice exposed to chronic hypoxia (CH) show higher basal PLC activity and [Ca²⁺]_i in PASMCs than that in MASMCs. A: lysates from PAs and MAs from mice exposed to CH for 3 wk were subjected to PLC activity assay. Data were obtained from four independent experiments. The data were obtained by taking the average of the test values in the normoxia group, dividing the individual value from each test in the normoxia and hypoxia groups by the averaged value from the normoxia group, and finally taking the average of the calculated values in the normoxia and hypoxia groups (B) to provide basal intracellular [Ca²⁺]_i in PASMCs and MASMCs. Data were obtained from four animals. *P < 0.05 compared with normoxia.