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. 2018 Jan 26;314(5):H1011–H1021. doi: 10.1152/ajpheart.00664.2017

Fig. 3.

Fig. 3.

Chronic hypoxia (CH) increases vasoconstrictor sensitivity to endothelin-1 (ET-1). Vasoconstriction (percent baseline internal diameter; A) and fura-2 ratios (B) in endothelium-disrupted, Ca2+-clamped control and CH pulmonary arteries in response to increasing concentrations of ET-1 are shown. n = 5–6/group. *P < 0.05 vs. control.