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. Author manuscript; available in PMC: 2018 Jun 19.
Published in final edited form as: J Alzheimers Dis. 2018;64(Suppl 1):S47–S105. doi: 10.3233/JAD-179932

Figure 4. Overview of the currently available technologies and the resulting biological marker categories used for biomarker discovery in preclinical and clinical research.

Figure 4

Abbreviations: CNV, copy number variations; FISH, fluorescence in situ hybridization; GCMS, gas chromatography mass spectrometry; HPLC, high-performance liquid chromatography; LCMS, liquid chromatography–mass spectrometry; NMR, nuclear magnetic resonance; PCR, polymerase chain reaction; SNPs, single nucleotide polymorphisms; SVs, structural variations. Reproduced with permission from [79].