Skip to main content
. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: J Immunol. 2018 May 11;201(1):278–295. doi: 10.4049/jimmunol.1701069

Figure 7.

Figure 7

Serum IL-7 levels and STAT5 signaling were reduced after IL-7 blockade. (A) Serum IL-7 levels were decreased after anti-IL-7 treatment. (B) and (C) Phospho-STAT5 was reduced after anti-IL-7 treatment in tumor-bearing mice. The percentages and cell numbers of Gr-1+CD11b+ MDSCs were elevated in the bone marrow (D) and lungs (F) after anti-IL-7 treatment in tumor-bearing mice. No changes of MDSCs were observed in the spleens (E) of tumor-bearing mice after anti-IL-7 treatment (n = 5 mice/group). *, P < 0.05; **, P < 0.01; ***, P < 0.001.