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Experimental protocols. Irradiation protocols comprised single dose irradiation (SD, arrow) or daily fractionated irradiation with 3 Gy per day (black square) over one (5 × 3 Gy) or two weeks (10 × 3 Gy), followed by graded top-up doses (SD, 5 dose groups, 10 animals each) on day 7 or 14, respectively. Irradiation was either applied alone or in combination with daily 4 mg/kg dermatan sulfate (DS) treatment over varying time intervals, illustrated by the shaded area
