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Differences in orientation in hemagglutinin (HA) complexes with WT (A) or D325A + R343V (B)—this figure represents the endpoints of three repeated simulations. Calcium ions are represented in orange, red, and white; WT and D325A + R343V are in transparent cartoon representation in green and purple, respectively; HA is shown in cartoon representation in cyan [this figure was reprinted with permission from Goh et al. (79)].
