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. 2018 Jun 13;12:398. doi: 10.3389/fnins.2018.00398

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Copyright © 2018 Yang, Tsai, Lin and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Percentage of estimation failure for sample entropy (SampEn) because of the absence of pattern matches in CSF BOLD signals. The percentage was calculated based on the CSF voxels with invalid SampEn relative to all CSF voxels in the entire study cohort. The percentage was compared with those of various combinations of m and r across all scale factors with different BOLD signal lengths. The more stringent combinations of m and r (i.e., higher m and lower r) and shorter BOLD signals resulted in a higher percentage of invalid SampEn estimations. Ideally, the choice of m and r should have valid SampEn estimations in all voxels.