Figure 4.

Genetic structure of com operon in human macrococci. The picture shows a comparison of the comG and comE operons, which might be functional in macrococcal strains CCM 4927^T, CCM 7099^T, and CCM 7100^T. The genes are annotated according to Fagerlund et al. (2014); ComGA is a traffic ATPase, ComGB a polytopic membrane protein and ComGC major component of a pilus ensuring the competence of bacterial cells during transformation. Genes comGD, comGE, and comGF encodes minor pilin structure. ComEA is a membrane DNA receptor, ComEB a late competence protein, and ComEC a channel for DNA uptake.