Table 4.

Final model for progression-free survival in the development cohort (UICC-8 staging was removed from the full model)

	HR	2.5%	97.5%	P
Age	1.01	1.01	1.02	<0.01
Gender, Female (ref)
Male	1.24	1.02	1.51	0.03
HPV–/p16– (ref)
HPV–/p16+	0.91	0.65	1.26	0.57
HPV+/p16–	0.75	0.52	1.09	0.13
HPV+/p16+	0.41	0.33	0.52	<0.01
Smoking, Current (ref)
Former	0.64	0.52	0.78	<0.01
Never	0.63	0.47	0.85	<0.01
T1 (ref)
T2	1.43	1.09	1.87	0.01
T3	1.81	1.36	2.41	<0.01
T4	3.10	2.27	4.25	<0.01
N0 (ref)
N1	1.17	0.92	1.50	0.20
N2	1.61	1.24	2.09	<0.01
N3	2.02	1.53	2.66	<0.01
M0 (ref)
M1	1.79	1.02	3.13	0.04