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. 2018 May 24;118(12):1672–1681. doi: 10.1038/s41416-018-0107-9

Table 4.

Final model for progression-free survival in the development cohort (UICC-8 staging was removed from the full model)

HR 2.5% 97.5% P
Age 1.01 1.01 1.02 <0.01
Gender, Female (ref)
 Male 1.24 1.02 1.51 0.03
HPV–/p16– (ref)
 HPV–/p16+ 0.91 0.65 1.26 0.57
 HPV+/p16– 0.75 0.52 1.09 0.13
 HPV+/p16+ 0.41 0.33 0.52 <0.01
Smoking, Current (ref)
 Former 0.64 0.52 0.78 <0.01
 Never 0.63 0.47 0.85 <0.01
T1 (ref)
 T2 1.43 1.09 1.87 0.01
 T3 1.81 1.36 2.41 <0.01
 T4 3.10 2.27 4.25 <0.01
N0 (ref)
 N1 1.17 0.92 1.50 0.20
 N2 1.61 1.24 2.09 <0.01
 N3 2.02 1.53 2.66 <0.01
M0 (ref)
 M1 1.79 1.02 3.13 0.04