Table 4.

Risk of obesity-related cancer in men and women according to change in weight status during middle age

Weight status change	N	Baseline BMIa	Follow-up BMIa	HR (95% CI)b
Men
Did not become overweightc	1389	25.6	26.2	1.00
Became overweightd	206	27.8	32.0	2.18 (1.33, 3.56)
Sustained overweighte	248	32.9	34.4	1.28 (0.76, 2.14)
Women
Did not become overweightc	970	21.5	22.4	1.00
Became overweightd	468	22.9	27.8	1.60 (1.12, 2.28)
Sustained overweighte	569	29.6	32.2	1.33 (0.94, 1.88)

BMI body mass index, CI confidence interval, HR hazards ratio.

^aMean BMI at baseline and at the end of weight change period (average follow-up of 14 years).

^bAdjusted for age, average adult height, education, cigarettes per day, alcohol intake and physical activity.

^cWomen with BMI <25 kg/m² and men with BMI <30 kg/m² at baseline who had no change in BMI category over ~14-year weight change period.

^dWomen with BMI <25 kg/m² at baseline who had BMI ≥25 kg/m² at the end of weight change period; men with BMI <30 kg/m² at baseline who developed BMI ≥30 kg/m² at the end of weight change period.

^eWomen with BMI ≥25 kg/m² and men with BMI ≥30 kg/m² at baseline who remained overweight throughout weight change period