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Tubular localization of iron handling proteins in the healthy kidney.
| Protein | Proximal tubule | Distal tubule | Tubular localization | ||
|---|---|---|---|---|---|
| Apical | Basolateral | Intracellular | |||
| ZIP8 | + | + | + | − | − |
| ZIP14 | + | + | − | − | + |
| DMT1 | + | + | + | − | + |
| L-ferritin | + | − | − | − | + |
| H-ferritin | + | − | − | − | + |
| Ferroportin | + | − | − | + | + |
DMT1, divalent metal transporter 1; +, present; −, not detected.
