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Pneumococcal LytR contributed to resistance to phagocytosis. D39ΔlytR + ΔTM-LytR: D39ΔlytR cells were grown in the presence of 500 ng LytR; D39ΔlytR + Ply: D39ΔlytR cells were grown in the presence of 500 ng Ply. D39 WT vs D39ΔlytR, P = 0.016; D39ΔlytR + LytR vs D39ΔlytR, P = 0.0052; ∗P < 0.05, ∗∗P < 0.01; NS: not significant. Three independent experiments were performed and the data represent means of three replicates ± standard deviations.
