FIGURE 1.

Crystal structures of FabG4: (A) N-terminal “flavodoxin type” (orange) and C-terminal ketoreductase (magenta) domains. “N” indicated the N-terminal of the polypeptide chain. The regions those were not be traced in electron density are shown in dotted lines. (B) The substrate mimic hexanoyl coenzyme A (HXC) and NAD+ bound structure shows the putative substrate binding modes.