Table 1.
Clinical characteristics of the study population.
| Healthy control | Untreated Graves' disease | Painless thyroiditis | Subacute thyroiditis | |
|---|---|---|---|---|
| Gender (M/F) | 17/49 | 25/101 | 6/30 | 5/13 |
| Age (years) | 48.05 ± 14.72 | 40.25 ± 12.49 | 40.00 ± 12.79 | 43.94 ± 7.36 |
| FT3 (pmol/L) | 4.04 ± 0.50 | 24.85 ± 14.02ab | 6.36 ± 2.74 | 9.69 ± 4.88 |
| FT4 (pmol/L) | 12.87 ± 1.39 | 36.26 ± 14.09ab | 19.48 ± 5.64 | 30.49 ± 11.08 |
| FT3/FT4 ratio | 0.32 ± 0.04 | 0.66 ± 0.26abc | 0.32 ± 0.07 | 0.31 ± 0.07 |
| TSH (mIU/L) | 1.83 (0.54–3.25) | 0.0006 (0.0001–0.01)a | 0.01 (0.0001–0.2927) | 0.0046 (0.0001–0.39) |
| TPOAb (IU/L) | 0.43 ± 0.59 | 444.33 ± 393.43ac | 336.45 ± 380.16 | 2.29 ± 3.59 |
| TgAb (IU/L) | 14.19 ± 87.19 | 221.29 ± 290.78ac | 207.87 ± 292.53 | 18.54 ± 31.78 |
| TRAb (IU/L) | 0.33 ± 0.08 | 15.51 ± 16.15abc | 0.60 ± 0.45 | 2.81 ± 8.71 |
Descriptive data were shown as mean ± SD for normally distributed continuous parameters, and for skewness distribution data, median and interquartile range was used. P < 0.05 were considered statistically significant. Differences between multiple groups were tested by one-way analysis of variance (ANOVA) and post hoc comparisons were performed using Tukey's tests. aSignificance difference between untreated GD and healthy control at P < 0.001. bSignificance difference between untreated GD and painless thyroiditis at P < 0.001. cSignificance difference between untreated GD and subacute thyroiditis at P < 0.001.