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A summary of the toxicity profile of ADT VMS.
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
|---|---|---|---|---|
| Sweats | 82 | 91 | 51 | 26 |
| Hot flushes | 84 | 91 | 53 | 22 |
| Sleep disturbances | 186 | 44 | 17 | 3 |
| Nervousness | 231 | 18 | 1 | 0 |
| Low mood | 203 | 40 | 7 | 0 |
| Tiredness/Fatigue | 150 | 79 | 19 | 2 |
| Joint pains | 200 | 41 | 9 | 0 |
| Headache | 238 | 12 | 0 | 0 |
| Palpitations | 241 | 8 | 1 | 0 |
| Unsteadiness | 231 | 17 | 2 | 0 |
